Zhang, P. and Cheung, P. C. Evaluation of sulfated Lentinus edodes alpha-(1-->3)-D-glucan as a potential antitumor agent. Int.J.Immunopharmacol. Destroy Cancer Cells. 2002;8(5):581-589. It should not be Int Immunopharmacol. Takemura, T., Takahashi, S., Yoshikawa, T., and Kondo, M. [A case of advanced gastric cancer (type 3) with pyloric stenosis, multiple liver and lymph node metastases responding to UFT-E granules and lentinan]. Enman, J., Rova, U., and Berglund, K. A. Quantification of the bioactive compound eritadenine in selected strains of shiitake mushroom (Lentinus edodes). [Pilot study of TS-1 combined with lentinan in patients with unresectable or recurrent advanced gastric cancer]. Cutis. Systemic allergic contact dermatitis due to consumption of raw shiitake mushroom. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Side Effects & Safety When taken by mouth: Shiitake mushroom is LIKELY SAFE when consumed in food amounts. Alder, oak, beech, and poplar are a few others that these may infect. 2005;5(5):811-820. View abstract. Takeshita, K., Saito, N., Sato, Y., Maruyama, M., Sunagawa, M., Habu, H., and Endo, M. [Diversity of complement activation by lentinan, an antitumor polysaccharide, in gastric cancer patients]. The material appearing on LIVESTRONG.COM is for educational use only. View abstract. View abstract. Biotherapy 1992;5(2):107-112. View abstract. Ueda A, Obama K, Aoyama K, et al. used as a substitute for professional medical advice, Hardening of the arteries (atherosclerosis). You may experience symptoms such as difficulty in breathing, swelling in neck, throat and face, elevated heart rate and hives. 2015 Mar-Apr;90(2):276-8. Kuznetsov, O. I., Mil'kova, E. V., Sosnina, A. E., and Sotnikova, N. I. Taguchi T. Clinical efficacy of lentinan on patients with stomach cancer: end point results of a four-year follow-up survey. Gastroenterol Rep (Oxf) 2019;7(4):298-300. doi: 10.1093/gastro/gox028. Research suggests that shiitake mushrooms help fight cancer cells and the … Nakano, H., Namatame, K., Nemoto, H., Motohashi, H., Nishiyama, K., and Kumada, K. A multi-institutional prospective study of lentinan in advanced gastric cancer patients with unresectable and recurrent diseases: effect on prolongation of survival and improvement of quality of life. Sastre, J., Ibanez, M. D., Lopez, M., and Lehrer, S. B. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Gan To Kagaku Ryoho 1986;13(4 Pt 2):1270-1276. Lingström P, Zaura E, Hassan H, et al. Taguchi, T., Furue, H., Kimura, T., Kondo, T., Hattori, T., Itoh, I., and Ogawa, N. [Results of phase III study of lentinan]. Information from this source is evidence-based and objective, and without commercial influence. Clin Toxicol (Phila). (check all that apply). Int.J.Immunopharmacol. Kan, N., Kodama, H., Hori, T., Takenaka, A., Yasumura, T., Kato, H., Ogawa, H., Ohsumi, K., Kudo, N., Mukaihara, S., and . WebMD does not provide medical advice, diagnosis or treatment. J Altern.Complement Med. Shiitake is used as an anti-cancer drug in Japan and sanctioned for this purpose by their FDA.It has many health benefits, such as it’s ability to lower blood pressure and reduce cholesterol. [10] Eosinophilic oesophagitis developed after intake of shiitake mushroom … Herlyn, D., Kaneko, Y., Powe, J., Aoki, T., and Koprowski, H. Monoclonal antibody-dependent murine macrophage-mediated cytotoxicity against human tumors is stimulated by lentinan. Shiitake mushroom is LIKELY SAFE when consumed by mouth in food amounts, but it seems POSSIBLY UNSAFE to take by mouth in medicinal amounts. View abstract. Sakamaki, S., Kohgo, Y., Suzuki, M., Ogiwara, R., Suga, T., Kondo, N., Izawa, M., Kanisawa, Y., and Niitsu, Y. II. You can see them on the outside of the host tree’s trunk. (Tokyo) 1987;35(6):2453-2458. Nowadays mushrooms are known as superfoods because of high nutrients and protein content. Gan To Kagaku Ryoho 1987;14(5 Pt 1):1342-1344. Hitosugi M, Kitamura O, Takatsu A, Yoshino Y. Autopsy case of duodenal obstruction from impacted mushroom. Mashiko, H., Satoh, J., Hatayama, H., and Kitamura, H. [A case of advanced gastric cancer with liver metastasis completely responding to a combined immunochemotherapy with UFT, mitomycin C and lentinan]. It makes your body being fatigue later. Privacy Policy 2011 Oct 5;3(2):e21. Postepy Dermatol Alergol. Biosci.Biotechnol.Biochem. However, this is a rare case and might happen due to handling or eating a raw mushroom. View abstract. Reishi mushrooms are generally considered safe but can come with some side effects and may interfere with certain medications. Kunitomo, K., Kawahito, M., Miura, M., and Komi, N. [Combination therapy with lentinan, mitomycin c, 5-fluorouracil and radiation--a case of long-term survival of pancreas cancer after palliative surgery]. , Shiitake mushrooms are generally safe for consumption though they can cause minor reactions in certain individuals. However, if you have a condition we talked about in this article, you should be aware. All rights reserved. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Nimura, H., Mitsumori, N., Takahashi, N., Kashimura, H., Takayama, S., Kashiwagi, H., and Yanaga, K. [S-1 combined with lentinan in patients with unresectable or recurrent gastric cancer]. Matsuoka H, Seo Y, Wakasugi H, et al. 1993;36(2):123-126. View abstract. Liu, M., Li, J., Kong, F., Lin, J., and Gao, Y. C haga is quite safe on side effects. 2015;54(5):e179-81. Wada T, Nishide T, Hatayama K, et al. 2012 May-Jun;87(3):463-5. Nippon Gan Chiryo Gakkai Shi 10-20-1982;17(7):1895-1901. [NK activity and T cell subsets in percutaneous ethanol injection therapy of liver cancer--effect of lentinan with combined use]. Fujiwara, K., Sato, T., Yonei, T., Genba, K., Nogami, N., and Yamadori, I. Shimizu, H., Inoue, M., Shimizu, C., Saito, J., Ueda, G., and Tanizawa, O. Augmentation of antitumor effect of recombinant interleukin-2 activated killer cells by the administration of rIL-2 and lentinan. Br J Gen Pract. Nakamura T. Shiitake (Lentinus edodes) dermatitis. Although reishi mushrooms are edible, they are mostly found as supplements in the form of capsules, powders, extracts and tinctures. View abstract. Int J Dermatol. Hanaue, H., Tokuda, Y., Machimura, T., Kamijoh, A., Kondo, Y., Ogoshi, K., Makuuchi, H., Nakasaki, H., Tajima, T., Mitomi, T., and . . One of the reported side effects of shiitake is developing skin rashes. 2014 Aug;64(625):426-7. The anticaries effect of a food extract (shiitake) in a short-term clinical study. View abstract. Wakui, A., Kasai, M., Konno, K., Abe, R., Kanamaru, R., Takahashi, K., Nakai, Y., Yoshida, Y., Koie, H., Masuda, H., and . J Am Acad Dermatol. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version.© Therapeutic Research Faculty . Bioorg.Med Chem 5-15-2003;11(10):2193-2203. View abstract. View abstract. It can cause stomach discomfort, blood abnormalities, and skin swelling (inflammation). Agric.Biol Chem 1990;54(2):479-487. Cancer Immunol.Immunother. JAAD Case Rep. 2015 May 2;1(3):117-9. Clinical features of shiitake dermatitis: a systematic review. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. But, anything that is proven to be beneficial is also limited to some extent and the same principle applies to mushrooms as well. View abstract. Champignon Noir, Champignon Parfumé, Champignon Shiitake, Champignons Shiitake, Forest Mushroom, Hongos Shiitake, Hua Gu, Lenticus edodes, Lentin, Lentin des Chênes, Lentin du Chêne, Lentinan edodes, Lentinula, Lentinula edodes, Lentinus edodes, Mushroom, Pasania Fungus, Shitake, Shiitake, Snake Butter, Tricholomopsis edodes, Xiang Gu. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Moreover, we do not select every advertiser or advertisement that appears on the web site-many of the pii: 13030/qt7rm57553. View abstract. View abstract. 2015;34(6):478-87. [Antimicrobial action of Lentinus edodes juice on human microflora]. Horiguchi, M., Saito, A., and Sonoda, H. [A gastric cancer showing marked improvement (stage IV) with lentinan immunotherapy and 5-FU, MMC-chemotherapy]. Biosci.Biotechnol.Biochem. Otsuka M, Shinozuka K, Hirata G, Kunitomo M. [Influences of a shiitake (Lentinus edodes)-fructo-oligosaccharide mixture (SK-204) on experimental pulmonary thrombosis in rats]. Eosinophilia and gastrointestinal symptoms after ingestion of shiitake mushrooms. Shiitake mushrooms can cause an allergic reaction in some individuals, which can adversely affect your skin, nose, throat, or lungs, according to the American Cancer Society. Antiviral Effects of Shiitake. It can also be made into soup or tea. Nishihira T, Akimoto M, Mori S. [Anti-cancer effects of BRMs associated with nutrition in cancer patients]. View abstract. View abstract. If you still decide to use a shiitake mushroom supplement, or add large quantities of shiitake mushrooms to your diet, consult your physician first. View abstract. Takeshita, K., Hayashi, S., Tani, M., Kando, F., Saito, N., and Endo, M. Monocyte function associated with intermittent lentinan therapy after resection of gastric cancer. Czarnecka AB, Kreft B, Marsch WCh. As with all supplements, be sure to talk to a doctor if you experience any side effects when using shiitake mushroom extract. 1985;7(5):747-751. 2017 Jun;56(6):610-616. Taguchi, T. [Effects of lentinan in advanced or recurrent cases of gastric, colorectal, and breast cancer]. View abstract. Though they are generally safe, consuming shiitake mushrooms in large quantities could disturb your digestive system. Keep in mind that natural products are not always necessarily safe and dosages can be important. View abstract. Mizuno, T. Shiitake, Lentinus edodes: functional properties for medicinal and food purposes. J Med 1998;29:305-30. Mushrooms are well known for their health benefits but on the other hand, it has some side effects also when consumed in excess or not fresh. Zakany, J., Chihara, G., and Fachet, J. Chu EY, Anand D, Dawn A, Elenitsas R, Adler DJ. Mak, R. K. and Wakelin, S. H. Shiitake dermatitis: the first case reported from a European country. View abstract. View abstract. How to … View abstract. Cutis. View abstract. Gan To Kagaku Ryoho 1987;14:516-22. Individual diversity of IL-6 generation by human monocytes with lentinan administration. View abstract. [Randomized study of lentinan on patients with advanced gastric and colorectal cancer. and View abstract. View abstract. View abstract. The reishi mushroom is popular in Eastern medicine and claimed to have various health benefits. Beneficial is also limited To some extent and the … a number studies! This information may not fit your specific health circumstances vitamins and supplements To avoid with hepatitis C.:., Li, J., Ibanez, M. Acting mechanisms of lentinan on patients with gastric carcinoma mellitus. And several other conditions Consumer Version we talked about in this article, you should aware. Chem 1990 ; 36 ( 1 ):107-111 CD, Talarico SR. shiitake dermatitis: shiitake mushroom side effects first reported..., Stingl G, Tanew a case series with clinical observations Rep. may! 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