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Talk with the doctor. So we cant say for sure whether the drug is safe to use while youre pregnant. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. This includes your doctors, nurses, pharmacists, and dentists. 5 0 obj Youll receive doses of either drug by a healthcare professional at a medical facility. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. If this happens, you may need to get another treatment course of Injectafer, if your doctor recommends it for you. Dizziness. This gives a total cumulative dose of 1,500 mg of Injectafer. It depends. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. Should I avoid certain foods while taking Venofer Vial? *Patients are calculated based on an estimated annual cumulative dose. There isnt a known interaction between Injectafer and alcohol. 4 0 obj It may also cause nervousness, restlessness, and difficulty sleeping in some people. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. This may be helped by giving the medication more slowly or at a lower dose. This website is intended for use by US patients. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. I can't take oral supplements because they cause horrible debilitating Constipation. In clinical trials,. (One treatment course includes two doses of the drug.) This can be very helpful in . Injectafer begins working as soon as it enters your body. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. fever. Canada residents can call a provincial poison control center. What is Venofer? In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Procedure Details Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. <> Cancer patients who have anemia and are taking an ESA. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. Injectafer comes as a liquid solution inside vials. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Many people using this medication do not have serious side effects. There are 2 tests that your doctor will likely Call your doctor for medical advice about side effects. This treatment course is split into two doses of the drug, which are given at least 7 days apart. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Then your body uses that iron to make hemoglobin and RBCs. And this could lead to weight gain, if they increase their food intake. (See also Notes section.). For some people, it may be OK to continue taking a multivitamin that contains iron. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Iron sucrose can also be mixed in a. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Do not flush down a toilet or pour down a drain unless you are told to do so. And these two doses need to be separated by at least 7 days. Notify your healthcare provider of any irritation at the injection site. They can tell you about other medications that may work well for you. Brand-name medications usually cost more than generics. If you notice any changes to your normal blood pressure, call your doctor right away. 3 0 obj Find out what health conditions may be a health risk when taken with Venofer Vial While the side effects that occur during treatment with these drugs are increasingly well-cataloged, the long-term side effects that may result from receiving these drugs are only beginning to be studied. I had my first infusion of 1gm 10 days ago. 2 Protocol for Intravenous iron sucrose - Venofer 2.1 Dosage The total cumulative dose of Venofer should be calculated using the table below. A healthcare provider will give you this injection. But they wont receive a total cumulative dose of more than 1,500 mg of Injectafer. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Be ready to tell or show what was taken, how much, and when it happened. Do not exceed 1,500 mg of iron per dosing course. But if they become more severe or dont go away, talk with your doctor or pharmacist. Available for Android and iOS devices. Instead, youll start by receiving just one treatment course of Injectafer. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. As a result, you may not make as much EPO as usual. Back pain. <> How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Injectafer contains the active drug ferric carboxymaltose, while Venofer contains the active drug iron sucrose. Details. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. dizziness. Back pain. An iron infusion is a way to increase the body's iron levels quickly. Some products that may interact with this drug include: vitamin products, other iron-containing products. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine. Undergoingcancer treatmentwithradiation therapyorchemotherapy drugsmay result inhair loss, which can be devastating to somepeople. This is not a complete list of side effects and others may occur. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. With anemia, you have a low level of red blood cells (RBCs) in your body. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. So theres no recommended pediatric dosage for Injectafer. Venofer may cause significant hypotension (decreased blood pressure). If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. As with most drugs, some people can have an allergic reaction after taking Injectafer. Examples of thisinclude: Not allside effectslast forever. But the length of time that this may take varies from person to person. If youre concerned about weight changes while youre taking Injectafer, talk with your doctor. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. US residents can call their local poison control center at 1-800-222-1222. Infusion times range from less than 20 minutes to up to 4 hours. upper respiratory infection. All rights reserved. Theseside effectscan range from being mild tosevere. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Its not known how common delayed allergic reaction might be in other people using Injectafer. This is why family members often have the same issues with drugs as others in theirfamily. Properly discard this product when it is expired or no longer needed. The Injectafer dosage your doctor prescribes will depend on your body weight. Learn more about the types of tests and treatment. Remember that it is best to get your vitamins and minerals from food whenever possible. Possibleside effectsareweight gainand suicidal thoughts. Low iron saturation, or iron deficiency, has various possible causes. If youre interested in finding an alternative to Injectafer, talk with your doctor. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. IQVIA [NSP Audit from MAT November 2013 to November 2018]. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Evenbirth controlcan lead to severeside effectslike bloodclots. All rights reserved. And this can lead to anemia, including IDA. Their medical staff can help you set up another time to receive your Injectafer dose. It is very important that your doctor check you closely while you are receiving this medicine. weakness. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. reese0809 1 yr. ago. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Your doctor will determine the best dosage to fit your needs. An LSD comedown is when the mental and hallucinatory effects have worn . The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Can poor sleep impact your weight loss goals? For more information about Injectafers approved uses, see the section Injectafer uses below. Side effectswill last a very long time if the cause of them is not resolved. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). Others last much longer (even a lifetime), which can be quite traumatizing to people. Tell your doctor if you are pregnant or plan to become pregnant. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Upset stomach or throwing up. (Hemoglobin is a protein thats found in your red blood cells.). Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. In clinical studies, people who took Injectafer had their hemoglobin level improve as early as 35 days after receiving treatment. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Serious side effects should be reported to a physician and/or PharmD for medical advice. With slow IV injection, the drug is given as a single, slow injection into your vein. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. In the US - Call your doctor for medical advice about side effects. This site is intended for use only by US patients. If you think there has been an overdose, call your poison control center or get medical care right away. Some may be a better fit for you than others. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Headache. Its responsible for carrying oxygen throughout your body. <> In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Iron infusions are given directly into a vein. Use of the term female in this article refers to sex assigned at birth. A lack of iron can lead to iron deficiency anaemia if left untreated. These people may lose weight as their anemia improves because theyre more active. Keep all regular medical and laboratory appointments. Keep all medications away from children and pets. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. The following lists contain some of the key side effects that may occur while taking Injectafer. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. With IDA, you have low hemoglobin levels. There have also been reports of serious allergic reactions to Venofer. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. Also tell them about any vitamins, herbs, and supplements you use. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. It belongs to a class of medications called iron replacement products. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. Venofer is given as an infusion into a vein. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. Throw away unused or expired drugs. Someside effectsare temporary or last as long as the person continues takingprescription medicine. During pregnancy, this medication should be used only when clearly needed. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Cardiovascular health: Insomnia linked to greater risk of heart attack. You may need extra iron because of blood loss during kidney dialysis. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. I had Venofer infusions, 2 rounds now in the span of three years. But you likely wont feel the drug working inside of you. Not all possible drug interactions are listed here. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. Injectafer helps to treat IDA by providing an iron infusion directly into your body. In the second group, some people switched from taking iron by mouth to taking Injectafer. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. Hemoglobin is a protein thats found inside your red blood cells. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. A delayed reaction can occur in two different ways: It can happen hours or days after you receive a drug, or it can happen after a second (or later) dose of a drug. ByDr. In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. For more information on the possible side effects of Injectafer, talk with your doctor or pharmacist. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. They can give you tips on how to deal with any side effects that may be bothersome. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. The drug helps increase your hemoglobin level back to a value thats within the normal range. Learn how to store and discard medical supplies safely. Examples of these side effects include dizziness and nausea. This medication is given by injection into a vein as directed by your doctor. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. Injectafer and Venofer are both brand-name drugs. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. taste impairment. (And Injectafer is used to treat IDA.) The infusion will take between 15-30 minutes if it is given in. However, diarrhea it isnt very common in people using Injectafer. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. One study of just under 5000 HRT users found that 43% were affected. With IV infusion, the drug is given as a slow drip into your vein over a period of time. With this condition, you also have a low hemoglobin level. People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. Before using, check this product visually for particles or discoloration. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Version: 7.01. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Follow all instructions closely. We comply with the HONcode standard for trustworthy health information. Use Venofer as ordered by your doctor. Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Dizziness. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. How long does iron infusion stay in your system? Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. For information on Injectafers effectiveness in treating IDA, see the Injectafer Uses section below. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. muscle pain. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. . And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body.